High glucosinolate broccoli: a delivery system for sulforaphane
نویسندگان
چکیده
منابع مشابه
Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli.
BACKGROUND Broccoli consumption is associated with a reduction in the risk of cancer, particularly in persons with a functional glutathione S-transferase M1 allele, as opposed rotrose whose GSTM1 gene has been deleted. Sulforaphane, the major isothiocyanate derived from 4-methylsulfinylbutyl glucosinolate, is thought to be the main agent conferring protection. OBJECTIVE We compared sulforapha...
متن کاملSulforaphane Glucosinolate Monograph
Introduction Intake of broccoli sprouts, a rich source of the glucosinolate glucoraphanin, has been associated with decreased incidence, multiplicity, and tumor growth in animal cancer models.1-3 In 1992, Paul Talalay, MD, and colleagues at Johns Hopkins University identified the isothiocyanate, sulforaphane, a biologically active metabolite of glucoraphanin, as the compound in broccoli respons...
متن کاملSulforaphane Glucosinolate Monograph
Introduction Intake of broccoli sprouts, a rich source of the glucosinolate glucoraphanin, has been associated with decreased incidence, multiplicity, and tumor growth in animal cancer models.1-3 In 1992, Paul Talalay, MD, and colleagues at Johns Hopkins University identified the isothiocyanate, sulforaphane, a biologically active metabolite of glucoraphanin, as the compound in broccoli respons...
متن کاملCultivation conditions and selenium fertilization alter the phenolic profile, glucosinolate, and sulforaphane content of broccoli.
Broccoli is a food often consumed for its potential health-promoting properties. The health benefits of broccoli are partly associated with secondary plant compounds that have bioactivity; glucosinolates and phenolic acids are two of the most abundant and important in broccoli. In an effort to determine how variety, stress, and production conditions affect the production of these bioactive comp...
متن کاملGas Chromatography/Mass Spectrometry Method for the Determination of Sulforaphane and Sulforaphane Nitrile in Broccoli
Phytochemicals, especially the secondary metabolites synthesized by plants, play key roles in human nutrition, health, wellness, and disease prevention. Some phytochemicals may be harmful to human health. For example, two closely related 4-methylsulfinylbutyl glucosinolate [glucoraphanin] hydrolysis products from broccoli (Brassica oleracea L. var. Botrytis), 1-isothiocyanato-4-(methylsulfinyl)...
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ژورنال
عنوان ژورنال: Molecular Breeding
سال: 2006
ISSN: 1380-3743,1572-9788
DOI: 10.1007/s11032-006-9029-y